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However, as prescription of semaglutide and similar medications escalated, anecdotal reports of reduced alcohol use became very common, and suggested the potential of these more potent therapies for treatment of alcohol use disorder. Research is needed to understand the mechanisms by which GLP-1 receptor agonists reduce alcohol cravings

Ellepola K, Truong T, Liu Y, Lin Q, Lim TK, Lee YM et al

Increased Heart Rate: Some patients may experience a slight increase in pulse during physical activity

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So, GLP-1 agonist medications could worsen the symptoms of gastroparesis by keeping food in the stomach even longer