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Under hypoxic conditions, SLC7A11 expression is reduced, whereas increases in MDA and Fe 2+ levels increase ROS accumulation in osteosarcoma cells

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Certain markers, like cancer antigen 125 (CA-125) and carcinoembryonic antigen cellular adhesion molecule-5 (CEACAM-5), already serve as serum tumor markers for pancreatic and ovarian cancers (282, 283)

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