doi: 10.1210/jendso/bvae015 15 JessupSKDimarakiEVSymonsKVBarkanAL
G6PD-deficient cells are unable to generate enough NADPH under the condition of severe thiol depletion and GSH biosynthesis and methionine cycle are upregulated at the expense of ATP but fail to compensate for GSH depletion (311)
Reported TB-500 side effects include fatigue, headaches, injection-site reactions, and appetite changes, but human safety research is very limited
The starting dose is typically 20 units (2mg)
Three times a day dosing Effect half half of 9.4 hrs Compared to reserpine, tetrabenazine has a more rapid onset of action, and more rapid reduction of side effects with dose reduction, making it easier to dose
Unlike garden-variety moodiness, depression is a serious condition that lasts for longer periods of time, and it affects 20% of women going through menopause