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Chromogranins: from discovery to current times

H., Zhu, X

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Despite advances in phenotypic and mechanistic characterization of three distinct permeability pathways, development of experimental agents that specifically target these pathways, and remarkable efficacy in preclinical models, pathway-targeted therapies have not been tested in human subjects

[2] Hydroxocobalamin is administered via intramuscular or intravenous injection to treat and prevent vitamin B deficiency, particularly in conditions like pernicious anemia where oral B absorption is impaired

All nine also appear on WADA's prohibited list for tested athletes