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The physician should provide information to the patient about the signs and symptoms of hepatotoxiciy that should cause alarm (e.g., nausea, fatigue, lethargy, pruritus, jaundice, right upper quadrant tenderness and "flu-like" symptoms)

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Peripheral neuropathy can be long-lasting, even permanent

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Common research areas include: NNMT enzyme pathway studies metabolic signaling research enzyme inhibition models biochemical pathway investigations cellular metabolism research In laboratory settings, researchers examine how modulation of metabolic enzymes may influence broader biochemical signaling networks