By simultaneously reducing inflammatory damage, enhancing cellular resilience, and promoting synapse formation, Dihexa addresses multiple pathological processes that contribute to cognitive decline, offering comprehensive neuroprotection rather than targeting a single disease mechanism
NHS access is expected later in 2026 following a NICE health technology assessment
Acetoacetate (A) is produced primarily by liver mitochondria where -hydroxybutyrate dehydrogenase is highly expressed, and maintains a ratio of -hydroxybutyrate () to A of about 2, reflective of the mitochondrial NADH to NAD ratio
The stack has a favorable safety profile when prescribed by a licensed provider and sourced from a reputable compounding pharmacy
Seasonality and symptoms of depression: A systematic review of the literature
So, if you cannot take the supplement on an empty stomach or you want the results to be spread throughout the day, then this is a good option