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Mechanistically, LONP1 silencing not only reduces cellular bioenergetic capacity but also decreases the LC3-II/I ratio and PINK1/Parkin levels, thereby suppressing mitophagy [169, 170] (Fig

Among the investigated compounds, GNF7156 and GNF4877 were screened as potential candidates for optimal beta cell proliferation (Shen et al

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36:13161323 [CrossRef] Gerlach M, Bartoszyk GD, Riederer P, Dean O, van den Buuse M (2011) Role of dopamine D3 and serotonin 5-HT 1A receptors in L: -DOPA-induced dyskinesias and effects of sarizotan in the 6-hydroxydopamine-lesioned rat model of Parkinsons disease

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