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In cancer cell lines lacking both ACLY and ACSS2, we show that a pool of cytosolic acetyl-CoA is maintained, that histone acetylation is active, and that both glucose and fatty acids can supply acetyl-CoA

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Brain Res 1056:168175 de Barreda EG, Prez M, Ramos PG et al (2010) Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits

Mitochondrial 12S rRNA encoding a 16-amino-acid peptide named MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) that regulates insulin sensitivity and metabolic homeostasis