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Beyond its cytoplasmic role, ATOX1 can translocate to the nucleus and function as a copper-dependent transcription factor, potentially regulating pathways such as HIF-1 signaling [93] (Figure 4)

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Skin-Brightening Advantages of Glutathione Glutathione shows promise in treating brightening skin and treating hyperpigmentation

It has been found to exert a wide array of beneficial effects, including anti-inflammatory properties and the ability to promote angiogenesis (the formation of new blood vessels), which is crucial for tissue repair and regeneration

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Recovery from ROS-induced toxicity was tested through MTT assay, in HeLa and SHSY-5Y cells pre-exposed to 10 M 3-AT for 15 min or 1 mM MPP + for 24 h respectively, followed by 250 M 15 min Sp treatment