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2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial

"These should be avoided if there is bloody stool, high fever, severe abdominal pain or concern for a more serious infection, because slowing the gut down can sometimes make illness worse." Note: Children should not be given these medicines unless a pediatrician recommends it

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Aronne LJ, Horn DB, le Roux CW, Ho W, Falcon BL, Gomez Valderas E, Das S, Lee CJ, Glass LC, Senyucel C, Dunn JP