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Although these findings are promising, further validation is required before clinical application

Caffeine is known as an ingredient that helps improve concentration and maintain energy

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Upon completion of this phase, cellular proliferation ceases and the follicle transitions into the catagen phase, during which programmed cell death (apoptosis) and keratinization processes lead to the involution of the lower follicle and the formation of a club-shaped hair structure

Katsumata R, Manabe N, Monobe Y, Tanikawa T, Ayaki M, Suehiro M et al (2022) Severe grade of melanosis coli is associated with a higher detection rate of colorectal adenoma

Arch Pharm (Weinheim) 1996