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Upon ligand binding, GLP-1R predominantly couples with Gs proteins to stimulate adenylate cyclase, leading to increased intracellular cAMP levels [32, 33]

Patients are usually started on a lower dose and gradually titrated up to help reduce side effects

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Caffeine is known to increase energy levels and slightly raise your metabolic rate

10.3389/fimmu.2018.00430 Front Immunol