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DiMarchi, who was a vice president at Eli Lilly and involved in GLP-1 research there, until he left the company in 2003, is that many diseases may share the same root causes, even though we label them and treat them as distinct: This is an endocrine disease, this is a cardiovascular disease, this is a brain disease. This root-cause theory suggests that a wide range of conditions can be treatable with one drug class, sometimes through pathways in the brain and the immune system
As GPCRs are ubiquitously expressed in all sensory neurons, this mechanism may be a general solution for efficient cellautonomous coding of external stimuli
The ameliorated oxidative stress and improved liver functions and structure in sesame oil-treated hypothyroid rats, as observed in this study, are consistent with those of Soliman et al
Glutathione levels decrease during the aging process
