[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Kaplan O, Firon M, Vivi A, Navon G, Tsarfaty I
Machine based topic/trend extraction has traditionally focused on variations of LSI (Latent Sematic Indexing), LDA (Latent Dirichlet Allocation) (Churchill and Singh 2022) or a simpler keyword evaluation of research papers (Nguyen et al
Key findings showed that NAC effectively lowered high triglycerides, insulin resistance, oxidative stress, and inflammation in the liver of the rats
Animal toxicology studies found no acute toxicity, organ damage, or reproductive toxicity across multiple routes and doses, but these studies lasted only up to 6 weeks
Over-the-counter anti-inflammatory medications (NSAIDs) and topical analgesics can provide short-term symptom relief for acute flare-ups
While these improvements were modest, they demonstrate that manipulating the gut can impact inflammation and cognition in AD