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Wolter, J.K

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keloid fibroblasts were prone to senescence following an ischemic stimulus, and FOXO4-DRI selectively induced the apoptosis of keloid senescent fibroblasts via p53-pS15 translocation from the nucleus to the cytoplasm

being the major increase in the GPx enzyme (approximately at 190 %), followed by GST enzyme (approximately at 170 %), GSH (approximately at 160 %), and finally GR enzyme (approximately at 140 %)