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Some sources report stability for up to 56 days, but 28 days is a safe guideline

Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8

A network of epigenomic and transcriptional cooperation encompassing an epigenomic master regulator in cancer

Special Populations Females have approximately 25% higher exposure to active metabolite than males

480 GiloteauxLO'NealACastro-MarreroJLevineSMHansonMR

Competing interests The authors declare that they have no competing interests.