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The clinical significance of this slight difference is debatable, but the effect is mentioned here as a possible off-target effect of DPP-4 inhibitors

This allows researchers to plan their experiments and projects

Contraindications and cautions include asthma (glutathione may trigger bronchospasm in sensitive individuals), platinum-based chemotherapy (glutathione may reduce drug efficacy), and certain genetic variations affecting cysteine and sulfur metabolism

10.1038/s42003-024-06226-1 16 ChengR.WangX.HuangL.LuZ.WuA.GuoS.et al (2024)

Persistent fatigue and low energy levels