Seek prompt medical attention if you experience pain in the upper right abdomen, pain radiating to the shoulder, yellowing of the skin or eyes (jaundice), or fever alongside abdominal pain
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The gradual increase is critical because adding too much fiber too quickly when your gut is already slow will cause painful bloating and gas
Observational research presented in March 2026 at the American Academy of Orthopaedic Surgeons annual meeting found that GLP-1 drugs may slightly increase the risk of developing osteoporosis and gout, a kind of inflammatory arthritis caused by a buildup of uric acid
Results vary from person to person, and the medication works best paired with sustainable nutrition and movement
Researchers looking for wider scientific context may find How Does Retatrutide Work? useful for research-led background around Retatrutide receptor pathway interest