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Covalent-Organic Frameworks Another well-known type of porous crystalline framework is covalent organic frameworks (COFs), which are a new class of network polymers formed by covalent bonds connecting organic building units, creating a structure composed of strong covalent bonds between elements such as B, C, N, O, and Si

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4) GI side effects and adherence: females appear more prone to GI AEs like nausea or vomiting during GLP-1 RA therapy, which can reduce caloric intake [57]