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Key safety concerns identified in Phase 2 data include elevated resting heart rate, gastrointestinal side effects, increased hypoglycaemia risk when combined with insulin or sulfonylureas, and class-relevant cautions around pancreatitis and thyroid C-cell tumours

Then, select one of the recommended injection areas

Retatrutide is currently undergoing phase 3 clinical trials, which will involve larger, more diverse populations and longer follow-up periods

And consistency is what separates medications that work from those that do not

The targets are the GLP-1 receptor (glucagon-like peptide-1), the GIP receptor (glucose-dependent insulinotropic polypeptide), and the glucagon receptor

Categorical variables were expressed in absolute frequencies and percentages, continuous parametric variables as mean and standard deviation (SD) and continuous non-parametric variables as median with inter-quartile range (IQR) or absolute range (AR) as appropriate