Taken together, these studies suggest that C-terminal truncated Syn variants may act as molecular decoy sequestering heterogeneous molecules, both proteins and membrane organelles, in their vicinity through nonfunctional interaction, leading to diffuse cellular aggregates or LB nucleation, as observed in various neurodegenerative disorders 83
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Psychosomatics 44:3843 Papadopoulos AS, Cleare AJ (2012) Hypothalamicpituitaryadrenal axis dysfunction in chronic fatigue syndrome