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These data are consistent with the results of our recent work where we found overactivation of mTORC1 signaling in the cortex of both ASD ( Shank3 InsG3680 (+/+) ) and AD ( P301S ) mouse models [176]

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These results collectively indicate that mitochondrial uncoupling with BAM15 has a powerful anti-obesity and insulin sensitization effect without affecting food intake

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.D'Antona G, Nisoli E