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After four weeks, the dose increases to 5mg weekly

Benchmarking against SUSTAIN-6 and SURPASS-CVOT In the emulation of SUSTAIN-6 comparing semaglutide to sitagliptin, a proxy for placebo, in patients at moderate and high cardiovascular risk (Table 2 and Supplementary Table 19), the hazard ratio (HR) for the primary endpoint was 0.68 (95% confidence interval (CI) 0.600.77) compared to the trial estimate of HR 0.74 (95% CI 0.58 to 0.95)

But because Wegovy and similar medicines like Zepbound and Saxenda come at such a high cost, the plan might soon drop coverage as a treatment for weight loss

The Mayo Clinic suggests aiming for 15.5 cups of fluids per day for men and 11.5 cups for women