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Higher doses dont have any clinical basis and may increase risk

People who are recovering from tendon, ligament, or muscle injuries, with persistent gut disorders (IBD, ulcers, leaky gut), inflammation or tissue damage from NSAIDs, wanting speedier surgery or injury recovery, managing brain-gut dysfunction or systemic inflammation

Proc Natl Acad Sci U S A 101:88412, PMID: 15187230 Into T, Inomata M, Nakashima M, Shibata K, Hcker H, Matsushita K (2008) Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses

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