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Evidence Limitations and Unanswered Questions The main evidence limitations for GHK-Cu are uneven human data, formulation differences, limited injectable safety information, small topical skin studies, indirect hair evidence, and uncertain long-term outcomes [2], [6], [7], [8]

Systemic copper toxicity is unlikely at recommended doses

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Meanwhile, genistein increased the levels of Nrf2, which is vital to the GSH system [132,133,134]

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