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2004;287(2):H812-7

Unlike retinoids, which have well-documented teratogenic effects and are contraindicated in pregnancy, copper peptides have no known mechanism for fetal harm

The pharmacokinetic properties including intestinal permeability, first-pass metabolism, microbiota-mediated biotransformation, plasma half-life, and systemic availability is essential for translational relevance

doi: 10.1136/vr.129.5.103

According to a recent study, the combination of chemical treatment with an FMD reduces the expression of heme oxygenase-1 (HO-1), which is a stress-responsive enzyme that protects cancer cells against oxidative damage and apoptosis in vivo

The aim of this selective compilation of a large body of research is to highlight the chemically plausible mechanisms through which some metals that are unable to react by the radical pathways related to the Fenton or Haber-Weiss reaction, are nevertheless able to generate a physiological damage by triggering oxidative stress through their reactivity towards the soluble thiolome pool