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Retatrutide, a novel GLP-1 drug in Phase 3, has not yet been approved by the FDA, restricting access to clinical environments and ruling out regular prescriptions in most locations

However, if you experience vaginal irritation and discomfort you think is happening because of your treatment, you should speak to your prescriber right away. Cosmetic differences, such as sagging skin, aside, Sivaraman said there are other changes to be mindful of

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Additionally, in an April 2025 interview with Ro, the NBA star shared that he had been unable to naturally drop the weight because his metabolism had changed with age, and he didn't have the stamina to hit the gym for hours