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10.1023/A:1021624520740
Nicotinamide N-methyltransferase: metabolic regulator and emerging therapeutic target (2024 review)
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[15] [16] Therapeutic uses [edit] SAMe has been studied for depression, osteoarthritis, and liver diseases with inconclusive results, and while generally considered safe short-term, its long-term safety, use during pregnancy, and risks for people with bipolar disorder or compromised immune systems remain unclear
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