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Interestingly it was observed the interaction between the main virus COVID-19 protease (responsible for virus replication) and antioxidant enzyme glutathione peroxidase-1, the enzyme-containing selenium in the catalytic center, and this interaction depends on selenium concentration, indicating the importance of selenium in the SARS-CoV-2 infection process (205)
The evolutionary distances were computed using the Poisson correction method and are in the units of the number of amino acid substitutions per site 43
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