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Medication Support: Over-the-counter anti-nausea medications or anti-diarrheal agents may be helpful but should only be used under medical supervision

LEADER trial: Cardiovascular outcomes with liraglutide JAMA Network Open (2022)

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As for the patient base, a recent report found that 75% of patients stop taking the medications within two years, although the report did not elaborate on the causes of this decline in use, which may be partially attributable to factors such as high costs and self-funding requirements

J Biol Chem 284(17):1160111612 Collinsova M, Strakova J, Jiracek J, Garrow TA (2006) Inhibition of Betaine-Homocysteine S-Methyltransferase causes hyperhomocysteinemia in mice

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