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Since the activity of enzymes involved in SNAC clearance may be lower in infants compared to adults, higher SNAC plasma levels may occur in neonates and infants

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Manufacturers and most clinical guidelines recommend against use pending further research

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Contrave may also cause serious mental health side effects such as psychosis, hallucinations, and paranoia

Pitfalls The nomogram may fail to predict the risk of hematotoxicity when any of the following confounders are present: Misleading history about the time of intoxication