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Under these conditions, FOXO4-DRI remains stable for the duration printed on the lot-specific COA

Given prior studies suggesting that the shortTL/highTA group represents a state in which the organism is unable to activate telomerase to an extent high enough to counteract the erosion of telomeres 81 , we planned to carry out post-hoc comparisons between this group and all other groups (Bonferroni corrected p value is 0.05/3 = 0.017)

As a reverse strategy, we used mice that express a catalytically inactive form of GPX4 (cysteine-variant

doi: 10.1186/s13071-018-2739-2 208 ScholmerichJ.FellermannK.SeiboldF