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In addition, acute swimming and short-term endurance training have been shown to upregulate serum GLP-1 secretion in healthy mice, leading to enhanced exercise performance (Wu et al., 2022)

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In 2023, the FDA removed 19 peptides from a list of drugs the agency allows compounding pharmacies to produce

However, the side effects associated with orlistat are not well tolerated and include flatulence, fecal urgency, and steatorrhea, restricting its use in the pediatric population

Table 1 Possible association between glucagon-like peptide 1 (GLP-1) and depression based on previous studies

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