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In the liver, the 25-hydroxylase enzymes (CYP2R1 and CYP27A1) convert inactive cholecalciferol to 25(OH)VD 3 (calcidiol) by carbon 25 hydroxylation 14

The PDE record contains prescription drug cost and payment data that enables CMS to make payment to plans and otherwise administer the Part D benefit, but CMS lacks the statutory authority to require physicians to include diagnosis information on prescriptions, which are generally governed by state law

Only selected effects of amylin are discussed here because we recently published extensive reviews on the physiology and pathophysiology of amylin

Am J Transl Res 16:68526866

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Comparative effectiveness of GLP-1 receptor agonists on cardiovascular outcomes among adults with type 2 diabetes and moderate cardiovascular risk: Emulation of a target trial