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The induction of GSTU7 and GSTF8 by SA was independent of the master regulator NPR1 gene

Modulating these pathways is therefore an area requiring careful characterisation in research

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Consequently, the SIRT1/Nrf2 signaling axis emerges as a critical pathway in maintaining chondrocyte integrity and attenuating the degenerative processes in the joint, offering a potential therapeutic strategy for managing osteoarthritis (Zhan et al., 2023