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Implications of VNS in obesity, MASLD, MASH, and cancer Given the complex interplay between metabolic dysregulation and obesity-related diseases, including metabolic-associated steatotic liver disease (MASLD), metabolic-associated steatohepatitis (MASH), and cancer, VNS offers a promising avenue for therapeutic intervention: VNS directly addresses the dysregulated energy balance by reducing appetite, enhancing satiety, and promoting metabolic efficiency

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