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And just before we move on to clinically assessing things outside of blood histamine, I did want to just ask you to share the why histamine intolerance is often more challenging or more prevalent in women, and youve kind of hinted at the estrogen connection there, but can you just give us a little bit more detail around that

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Within the TCA cycle, succinate is converted into fumarate by the succinate dehydrogenase (SDH) which represents the respiratory ETC complex II (CII) 73 (Supplementary Fig

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