The primary function of glutathione peroxidases is to protect the body from damage caused by oxygen free radicals, and each enzyme has a specific location (105, 106)
In such studies, the omics technologies are used to predict interaction between nanoparticles and biological systems, facilitate assessment of systemic toxicity due to nanomaterials, reveal potential strategies for risk mitigation
The non-hormonal mechanism makes them safe to use alongside hormone therapy if desired
Future research needs to integrate nutrigenomics, metabolomics and microbiome profiling to develop individualized nutrition plans based on the genetic and metabolic signature of women with PCOS
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Ultrathin sections were obtained by using a Leica ultramicrotome (Leica Microsystems, Buffalo Grove, IL, USA) and double-stained with uranyl acetate and lead citrate (Spi-Chem, USA)