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Multiple strategies have been proposed to circumvent the neuropsychiatric adverse effects including biased signaling, allosteric modulators, neutral antagonists, and peripherally restricted ligands since several metabolic processes appear to benefit from peripheral blockade of CB1 (113115)

Within this category, the age-adjusted prevalence for MASLD was 31.9% (95% CI 30.433.4), MetALD 2.2% (95% CI 1.82.6), and ALD 0.8% (95% CI 0.61.1)

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Acta Pharm Sin B 2022;12:2443-61.ArticlePubMedPMC 116

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