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Studies have shown that excessive activation of lipolysis through autoreflexes increases the level of free fatty acids in patients with severe obesity

Additionally, side effects such as nausea, vomiting, and diarrheacommon with GLP-1RAscould further decrease appetite and reinforce dietary restriction and dietary restraint

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(2023) 325:C66181

Therefore, exquisite regulation of these factors is imperative to maintain normal physiological conditions, derangement of which will cause manifestation of diseases

Although participants received standardized counseling regarding physical activity, levels of physical activity were not objectively collected