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Neuropsychiatric Disease and Treatment

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Authors contributions Study concept and design (GYW), drafting of the manuscript (EMY, GYW), literature review and writing of the manuscript (EMY), critical revision of the manuscript for important intellectual content (GYW), manuscript proofreading (GYW, EMY)

employed DNPH as a reactive matrix in MALDI-MS to detect peptides modified by 4-hydroxy-2-nonenal (HNE) in undigested samples, achieving the selective detection of modified peptides through the high D/I yield of hydrazone derivatives (Michael adducts with dinitrophenylhydrazine) (Figure )

Self-adjustment can lead to dangerous fluctuations in blood glucose levels, potentially resulting in hypoglycaemia or inadequate diabetes control

It also slows gastric emptying which makes you feel fuller sooner and longer