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This absence of IGF-1 stimulation is critical for appetite neutrality because IGF-1 has known effects on hypothalamic neuropeptide expression, including alterations to neuropeptide Y (NPY) and agouti-related peptide (AgRP), both potent appetite stimulators

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4.5 Anti-inflammatory Activity of GHK-Cu 4.5 Anti-inflammatory Activity of GHK-Cu As stated above, inflammation is one of the factors that can disrupt wound healing and trigger abnormal cell plasticity