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MDA, a reactive aldehyde, belongs to a class of reactive electrophile species that induce toxic stress in cells and form covalent protein adducts known as advanced lipoxidation end products, similar to advanced glycation end products

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Patients with pre-existing gastrointestinal conditionsinflammatory bowel disease, irritable bowel syndrome, or previous bowel surgeryshould maintain closer monitoring and lower thresholds for seeking medical input, as these populations may experience more pronounced or complex digestive effects