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0.55 M), metformin (Cayman Chemicals, 13118

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Specifically, quantitative analysis revealed that the relative average density (AOD) of CD31 was 1.48-fold higher in the G/D-CuP group than in the G/M-CuP group

Although SNP and NPH had the same dosage of OA-NPs, there was still a certain gap between the therapeutic effect of SNP and NPH in vivo, because NPH delivered more OA to the lesional site, thus playing a greater pharmacological role