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Using multiple high-throughput proteomics assays in two independent cohorts of konzo-affected children compared to unrelated individuals (Discovery) or their unaffected sibling (Validation) respectively, we demonstrate that levels of the critical plasma-based antioxidant enzyme Glutathione Peroxidase 3 (GPx3) are significantly reduced in those affected

Always consult a qualified healthcare provider before starting any new therapy

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To mitigate these risks, comprehensive in vitro and in vivo studies evaluating the immunogenic potential of peptide compounds should be conducted before initiating clinical trials

The company is exploring alternative methods of administering GLP-1 medications beyond injectables, with the goal of achieving scalable production to reach a wider population, said Karla Alcazar, President and General Manager, Lilly Latin America, during Mexico Health Summit 2025.