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What to do: Drink at least 1.5 to 2 litres of water daily , unless otherwise advised by your doctor Spread fluid intake throughout the day Include hydrating foods like soups and fresh fruit 5

doi: 10.1111/bjd.15550 14 RichmondJMStrassnerJPRashighiMAgarwalPGargMEssienKIet al

Curcumin, at doses that achieve a hormetic effect (e.g., 10 mg/L or approximately 28 M in vitro ), can enhance antioxidant defense by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, upregulating glutathione (GSH) metabolism, and inducing glutathione S-transferase (GST) activity, particularly isoforms involved in detoxifying lipid peroxidation products such as 4-hydroxynonenal (4-HNE)

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More extensive disease leads to abscess formation and rarely, with rupture, to peritonitis