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In the clinical trials so far, blood sugar effects have been manageable (retatrutide actually improved blood sugar in diabetic patients), and muscle loss has been proportional to weight loss

In addition to levothyroxine, there are other treatment options available for those with thyroid disorders

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By mimicking the natural incretin hormone GLP-1, these medications activate specific receptors throughout the body, triggering glucose-dependent insulin secretion, suppressing glucagon release, slowing gastric emptying, and modulating appetite centres in the brain

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