More than a century later, the company became a leader in incretin biology, building the GLP-1/GIP dual agonist tirzepatide (Mounjaro/Zepbound) and following it with retatrutide and orforglipron, its oral non-peptide GLP-1 program
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Theres also evidence that GLP-1s affect reward pathways in the brain
Tirzepatide has been shown to significantly reduce inflammatory markers including hsCRP and IL-6 in clinical studies
Medical Doctors (MDs) and Doctors of Osteopathic Medicine (DOs) can prescribe GLP-1 weight loss medications in all 50 states via telehealth, provided theyre licensed in the state where youre physically located during the consultation
Participants taking semaglutide showed significant reductions in major cardiovascular events, including heart attack and stroke, compared to placebo