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This neurobiological reset explains why many patients experience sustained appetite control even after reaching their goal weight

doi: 10.1371/journal.pone.0107612 35 BogaertD.HermansP

Efficacy and safety of once-weekly semaglutide 2.4 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 trial

1 The most recent clinical trial, SURMOUNT-1, reports that the average weight loss among over 2500 trial participants was 16% at 72 weeks