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Making Sense of Incretin Science Understanding the difference between GLP-1 and GIP helps demystify why certain weight loss medications work better than others

John Goodman John Goodmans dramatic weight loss transformation raised questions about how he managed to do so

GLP-1 agonists mimic the GLP-1 hormone by binding to GLP receptors and triggering the same effects

Many believe it does

These medications work by mimicking the action of naturally occurring GLP-1, an incretin hormone produced in the intestine that regulates blood glucose levels and appetite

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